Cassandra Voices

Tag: Vaccination

  • Covid-19: A New Irish Social Contract?

    Surveying the demise of the Celtic Tiger, Fintan O’Toole devoted an opening essay ‘‘Do you know what a republic is?’ The Adventure and Misadventure of an Idea’ in Up the Republic! Towards a New Ireland (2012) to assessing the health of the Irish Republic. He considered its vitality based on the presence, or otherwise, of three indicators: Non-Domination; Mixed Government and tolerance of Obstreperous Citizens.

    These features of a healthy republic, he wrote, diverge from a narrow form of republicanism associated with Rousseau ‘which argues for the notion of a single, sovereign popular will: ‘the People’ effectively taking the place of the king in a monarchy.’ Up to that point in Ireland, O’Toole argued, this latter, narrow version had predominated, which he associated ‘in vulgar terms’ with appeals being made to ‘pull on the green jersey’’; and where ‘an idea of accountability implicit in mixed government is ditched.’

    ‘For most of the history of the state’, O’Toole concluded that the state ‘failed miserably in the basic task of ensuring citizens were free from subjection to the arbitrary will of others.’[i]

    Now, as Ireland slowly unwinds from an interminable lockdown that tendency of Irish governments to pull on the green jersey, avoid accountability, reject obstreperousness and a conspicuous failure to ensure that citizens are free from the subjection to the arbitrary will of others, is evident once again. This regression has arrived especially through what O’Toole himself described on April 28th, 2020 as the ‘top-down, command-and-control approach’ of the National Public Health Emergency Team (NPHET), which the elected government has deferred to throughout most of the pandemic.

    Times of War

    The COVID-19 pandemic is likely to reshape the Irish political landscape, eroding foundational certainties of left and right. When the dust settles new formations may crawl from the debris, with democracy itself in peril, as the coalition government chooses to extend emergency powers until November, while other countries such as Denmark aim for a swift return to normality.

    In terms of the pandemic’s wide-ranging impact, there are parallels with the outbreak of a global war. As Hannah Arendt put it: ‘The days before and the days after the first World War are separated not like the end of the an old and the beginning of a new period, but like the day before and the day after an explosion.’[ii]

    Placing billions under lockdown around the world had a shuddering effect on daily routines, altering intimate exchanges and gestures, besides radically reducing the ambit of daily peregrinations. It’s a very modern form of trench warfare that confined most of us to within 5km of barracks – spilling out invective on (anti-)social media.

    In Ireland, with the advent of bigger government, there is a confidence among some on the left that their time has arrived, and that a relatively youthful population will vanquish age-old privileges of wealth and caste through a permanently enlarged state.

    However, as Eric Hobsbawm records, one reason Engels (and even the late Marx) ‘began to turn away from calculations that the international war might be an instrument of revolution was the discovery that it would lead to ‘the recrudescence of chauvinism in all countries’ which would serve the ruling classes.’[iii]

    Similarly, nationalism chauvinism – ‘excessive or prejudiced support for one’s own cause, group, or sex’ – has been witnessed throughout the pandemic in Ireland. This is perhaps unsurprising as, historically, infectious diseases have given rise to, and fed, plagues of prejudice and outright racism; the diseased ‘other’ at the gates of the city is a recurring theme. Ruling classes have often put forward strongman rulers to harness this xenophobic sentiment.

    Since March 2020 we have poured over spreadsheets of daily deaths, infections, testing rates and vaccine roll outs to determine how ‘we’ are doing relative to ‘them.’ In Ireland we tend to measure achievements and failures against the noisy neighbour next door, whose boorish leader has somehow managed to transform one of the world’s highest death tolls per capita from Covid-19 into a great British victory pageant, through a rapid vaccine rollout. Boris now looks unassailable, notwithstanding Brexit storm clouds, Dominic’s revenge, Indian variants; and just the suspicion that the vaccine may not prove quite the panacea it seems now in winter 2022. Time will tell.

    Indeed, the narrative arc of Boris Johnson’s response to the pandemic should serve as a warning to the Irish left that ruling classes can easily steal their best clothes. In this respect, Johnson operated with far greater flexibility than Donald Trump, shifting from a ‘take on the chin’ herd immunity approach in March, 2020 to championing what he would have previously decried as a ‘nanny state’ lockdown. He and his chumocracy used the pandemic as a pretext for introducing draconian legislation against protest and civil disobedience, apparently aimed at movements such as Extinction Rebellion.

    Recovery Position

    Similarly, though less dramatically, Leo Varadkar resuscitated his political career after Fine Gael’s disastrous performance in General Election 2020, donning proverbial scrubs for the initial phase of the pandemic. Having identified himself with “early-rising” middle class voters Varadkar was smart enough to realise that his preferred Thatcherite policy of reliance on an Invisible Hand of market forces could lead to a public health disaster during a pandemic.

    Since entering the coalition, Fine Gael Ministers have emphasised a law and order approach – Simon ‘TikTok’ Harris was quick off the blocks denouncing as ‘disgusting, grotesque and obscene’ a comparatively unobstreperous anti-lockdown protest in Dublin by European standards. Fine Gael have also allowed Fianna Fail to act as a mudguard for a failing system of public health: Ireland’s health expenditure is the third highest in the EU, yet we have only 5 ICU beds per 100,000, compared to 35 in Germany and 28 in Austria.

    Fine Gael represents itself as a centrist party, placing emphasis on its belated support for marriage equality and abortion referendums, which obscures from a failure in government to address structural inequalities and ongoing environmental damage. Replacing James Reilly as Minister for Health in 2015 Leo Varadkar promptly abandoned universal health insurance (UHI).

    After becoming leader of Fine Gael and Taoiseach, Leo Varadkar claimed he would represent thrusting early risers – tantamount to saying he would not alter structural inequalities that are most apparent in access to housing. In combination with Fianna Fail, Fine Gael has represented the dominant interest of large property owners, indifferent to whether their wealth is maintained via independent corporate entities, the state, or as in Ireland’s case increasingly, a corporate-state nexus.

    Simple distinctions of left and right are often misleading. Thus, when considering the virtues, or otherwise, of big government it should be clear that administrative levers and patronage may drive inequality; most obviously through mind-boggling salaries, such as the €420k paid to the Director General of a dysfunctional HSE, Paul Reid – ironically a former Workers’ Party activist. Reid has no medical or scientific qualifications, and previously acted as chief executive of Fingal County Council.

    Moreover, left-wing politicians and their supporters are often drawn from higher income groups; a tendency that within Fine Gael circles used to be referred to as noblesse oblige – accompanied by the obligatory glass of fine Cognac – of which the Just Society was the apotheosis. But a left-wing identity may be superficial, as the distribution of state largesse, or patronage, apart from being expressed in high public sector salaries, often benefits established professional elites of lawyers, academics and indeed doctors.

    Leprechaun Economics

    Big government patronage motors along fine in Ireland for all concerned as long as the tech and pharma sectors do the heavy economic lifting. This is the ‘Leprechaun Economics’ that Paul Krugman referred to dismissively. But now the Biden administration’s taxation proposed changes to the global tax system may make the current Irish model unworkable. The ECB is also likely to desist eventually from quantitative easing, with inflation looming.

    Renewed fiscal rectitude and the prospect of multinationals leaving a perpetually unaffordable capital city for workers, will place increasing reliance on those indigenous SMEs that have endured the Crash of 2008, and the unprecedented challenges of the pandemic. Yet whole sectors have been furloughed for over a year, with some such as events and tourism wondering whether they have a future at all. The Central Bank has warned that one in four firms could fail when pandemic payments cease.

    It should be unsurprising, therefore, for a small businessperson living from transaction to transaction to be wary of parties promising higher taxation on the left, and instead be attracted to politicians on the right, or even far-right, that are acquainted with the language of commerce, however superficial this may be, in the case of Leo Varadkar at least, whose concern for SMEs has disappeared after his supportive comments proved unpopular last October.

    An objective for a progressive left should be to attract support from an increasingly marginalised mercantile class, emphasising that a favourable environment for entrepreneurship, as in Scandinavia, is enabled by efficient public service, including a one-tier, functioning health system. The left can argue that leaving healthcare to market forces – as in the U.S. – is not only deeply unfair, but also, crucially, leads to greater costs than a functioning one tier public system which also – as in most European countries – delivers better outcomes overall.

    The inherent danger of Ireland’s two-tier model, where health care provision is subject to market forces is epitomised by a question recently posed by a Goldman Sachs executive: “Is curing patients a sustainable business model?” In an age of profound health insecurities – which are amplified through subtle advertising cues – market forces will continue to distort public health priorities.

    It was the father of economics Adam Smith who warned: ‘People of the same trade seldom meet together, even for merriment and diversion, but the conversation ends in a conspiracy against the public, or in some contrivance to raise prices.’ However, while resisting a buccaneering tendency in the delivery of a vital government service such as healthcare, the left cannot afford to dismiss the dynamism of entrepreneurship in society at large. Just imagine the food you would be served if the government was running all the restaurants.

    Following Public Health Guidance

    While there are a range of financial supports available to SMEs, the world-beating length of Ireland’s lockdown has made trade impossible for many businesses, some of which may never recover. The failure of the two centre-right parties in government to represent their concerns arguably, lies at the heart of Ireland’s deeply flawed response to the pandemic.

    From March to June, 2020, 96% of additional deaths related to COVID-19 in Europe occurred in patients aged older than 70 years. Yet, despite having the youngest population in the Union, according to a Reuters by February Ireland had endured 163 days of workday closures. This was the highest, by some measure, of all the European countries surveyed at that point. By contrast, Denmark had lost just fifteen days, having experienced a death toll almost half that of Ireland’s per capita.

    The uncritical attitude of mainstream Irish left wing parties towards public health officials should also be reconsidered. Recall the major mistakes in particular by Chief Medical Officer Tony Holohan, who saw nothing wrong with fans going to Cheltenham in early March, 2020, ordered care homes to re-open to visitors that same month, and then transferred 4,500 untested patients back into care homes – surely contributing to the second highest level of care home mortality in the world during the first wave. Yet Irish left wing politicians have consistently complained about the government failing ‘to follow public health advice,’ despite Holohan’s long history of cock-ups and cover-ups.

    Even before Christmas NPHET – a body composed primarily of career civil servants and notably short on scientific expertise – seemed to have been all on board for the ’meaningful Christmas’ of Micheal Martin’s imagination. The only significant deviation between the government’s approach and NPHET’s advice was that the latter preferred to permit household gatherings rather than opening the hospitality sector. Cue raucous Christmas house parties, as opposed to what were mainly orderly affairs in pubs and restaurants.

    In fact, Ireland’s ‘third’ wave, which coincided with the more transmissible B.119 variant (although apparently not more lethal as was widely reported) actually commenced in week 48 of 2020 (22/11/2020), while the country was still under Level 5 Lockdown restrictions, according to a report by the HSPC.

    Sadly, public health obscurantism has also brought denial of their own data, which said outdoor transmission of Covid-19 is about as frequent as curlew sightings.

    The latest embarrassment over NPHET refusing to acknowledge the benefits of antigen testing, underlines that if left-wing politicians are slavishly going ‘to follow the public health advice,’ and whatever Yes Minister civil servant advises then we won’t see radical reforms in Ireland any time soon.

    Frank O’Connor

    Guests of the Nation

    Over the course of the pandemic Irish attitudes have hardened against the free movement of people in and out of the country, culminating in the introduction of mandatory hotel quarantines for some foreign, including EU, arrivals at the end of February.

    Contemporary Irish attitudes to hardworking foreigners resident in Ireland recall Frank O’Connor’s classic 1931 short story ‘Guests of the Nation.’ Set during the War of Independence 1919-21 it portrays a bond of friendship that grows up between two IRA men, Bonaparte (the narrator), and Noble, who are detailed to guard two captured English soldiers Belcher and ‘Awkins who have a natural affinity with the country:

    I couldn’t at the time see the point of me and Noble being with Belcher and ‘Awkins at all, for it was  and is my fixed belief you could have planted that pair in any untended spot from this to Claregalway and they’d have stayed put and flourished like a native weed.

    Ultimately ‘Awkins and Belcher are sacrificed at the altar of of a narrow nationalism, just as a today the Populist appeal to ‘protect our own people’ has ordained that the rights of immigrants in Ireland, and abroad, to see their families was disregarded.

    This appears to stem from a widespread notion that ‘we,’ like faraway New Zealand and Australia, can eliminate the disease from ‘our’ shores altogether – devolving into the juvenile #wecanbezeros hashtag adopted by some politicians on the left. The problem is that ‘we’ are a society with lots of ‘them’ immigrants living here, and an enormous diaspora of ‘us’ beyond the shores of an island divided into two jurisdictions, highly dependent on international trade in goods arriving on trucks (with drivers).

    Moreover, apart from the extreme geographic isolation and sparse populations of Australia and New Zealand, ‘we’ in Ireland have legal obligations to preserve freedom of movement under European treaties and the Good Friday Agreement, enshrining a porous open land border. Apart from committing economic hari-kari, pursuit of ZeroCovid appears legally impossible, unless of course we want to pursue an Irexit and build a wall along the Northern border.

    Nonetheless, egged on by febrile – ‘if it bleeds it leads’ – coverage in a national media increasingly reliant on government advertising, a prevailing view is that all deaths from Covid are essentially preventable; emanating from the failing of the state, or the reviled Covidiot, rather than being the tragic consequence of a pandemic, the death toll from which has been systematically exaggerated.

    Moreover, intercepted correspondence within the ZeroCovid ISAG group of independent scientists – who have taken on the Opus Dei role to the Catholic hierarchy of NPHET – reveals, among other disturbing insights, that they were looking ‘for ways to increase insecurity, anxiety and uncertainty.’ As these revelations first appeared in right-wing Gript, however, the left-wing echo chamber refuses to acknowledge it is being played.

    Are you right there Michael?

    Nonetheless, a number of politicians have come forward representing an anti-authoritarian left, concerned by the harms of lockdown and favouring a targeted approach – protecting the elderly – and building up ICU capacity. In a recent blistering Twitter attack the independent (and former Labour) TD for Clare, barrister Michael McNamara – who as chair of the Oireachtas Committee on Covid-19 Response became as well acquainted as any Irish politician with diverging epidemiological assessments of the pandemic – identified a recurring Irish deference to vested authority.

    In response to a Fintan O’Toole article critiquing the DUP McNamara wrote: ‘Instead of criticising unionism, let’s look at the complete mess we’ve made of Irish nationalism and nationhood. We’re ruled by a junta of medics, just as we were Rome Ruled for 7 decades. The Orthodoxy changes but the crawthumping remains the same.’

    He continued: ‘If it wasn’t for Unionism, we’d be like Hoxha’s Albania now. There’d be no way off this island. But there is a beacon. Belfast Airport and Larne are beyond the reach of NPHET, just as surely as the rule of the Archbishop’s palace in Drumcondra didn’t pass the bridge in Portadown.’

    He added more controversially:

    ‘We can’t blame the medics for their experimental therapy, any more than we could blame the clergy for their zeal.  Successive governments have abdicated their democratic responsibility throughout this State’s short history. So why would Unionists want to be “governed” by Dublin?’

    It was a fair question, when one considers the North is reopening far sooner than the Republic. Although this has arrived after a rapid vaccine rollout, the experimental nature of which McNamara raises problems with.

    Facing Up to Errors

    Here we come to the crux of an unhelpful cultural division between left and right that the ruling parties will use to divide and conquer. This is the new identity politics arising out of the pandemic, epitomised by attitudes towards face masks.

    For too many on the left the science on this issue is proven as opposed to followed. Wearing a face mask now appears to have become an article of faith. Yet a recent report by the European Centre for Disease Control and Prevention entitled ‘Using face masks in the community: first update – Effectiveness in reducing transmission of COVID-19’ stated:

    The evidence regarding the effectiveness of medical face masks for the prevention of COVID-19 in the community is compatible with a small to moderate protective effect, but there are still significant uncertainties about the size of this effect. Evidence for the effectiveness of non-medical face masks, face shields/visors and respirators in the community is scarce and of very low certainty.

    Additional high-quality studies are needed to assess the relevance of the use of medical face masks in the COVID-19 pandemic.

    Moreover, the Irish left should consider our dependence on pharmaceutical behemoths that jealously guard intellectual properties, notwithstanding huge state aid grants, and indemnification against adverse reactions. It is akin to the dependence of small farmers in developing countries on genetically modified seed, under a model of Philanthrocapitalism overseen by Bill Gates, who according to a recent article by Alexander Zaitchik has shown “a lifelong ideological commitment to knowledge monopolies,” and devotes hundreds of millions of dollars each year to whitewashing his reputation through “charitable” media grants.

    Moreover, all too often, media debates around Covid-19 fail to acknowledge the link between pre-existing morbidities – ‘underlying conditions’ – and morbidity and mortality from Covid-19. Thus, US Studies have shown that having a BMI over 30—the threshold that defines obesity—increases the risk of being admitted to hospital with covid-19 by 113%, of being admitted to intensive care by 74%, and of dying by 48%, making it almost as relevant a consideration as having been vaccinated.

    In Ireland, moreover, Mayo coroner Patrick O’Connor recently questioned the attribution of deaths to Covid-19, saying: ‘In reality, a lot of people have terminal cancer or multiple other serious co-morbidities. People can die from Covid and or with Covid. I think numbers that are recorded as Covid deaths may be inaccurate and do not have a scientific basis.’

    https://twitter.com/SunTimesIreland/status/1383791062846562307

    Furthermore, by embracing ZeroCovid Utopianism many on the Irish left failed to focus on the failings of a decrepit Irish health system. This epitomises a tendency among politicians to dance to the tune of a corporate media that has placed relentless focus on the disease itself, regularly interviewing mendacious ISAG figures, while generally ignoring underlying social and environmental factors that drive morbidity and mortality.

    The canard that Ireland could simply shut its borders and reach ZeroCovid perhaps points to the need for reform of an Irish secondary educational system, which according to the a rather unkind assessment from the OECD’s Andreas Schleicher is designed to produce ‘second-class robots.’ Perhaps too many of us are lacking the requisite critical faculties to look beyond news headlines.

    In fact a radically different, defiantly left-wing approach to the pandemic been put forward by, among others, Harvard epidemiologists Katherine Yih and Martin Kuldorff in The Jacobin. They pointed out:

    Elites have seen their stock portfolios balloon in value, and many professionals have been able to keep their jobs by working from home. It is the country’s poor and working-class households, particularly those with children, who have borne a disproportionate share of the burden. Lower-income Americans were much more likely to be forced to work in unsafe conditions, to have lost their livelihoods due to business and school shutdowns, or to be unable to learn remotely.

    Beyond ZeroCovid, the Irish left should emphasis the harms of Ireland’s reliance on lockdowns, and harness the malcontents of the poorest, including small business owners. Otherwise they court irrelevance as the traditional ruling parties have already taken on the role of ‘caring’ for the people, while retaining the power to ease restrictions in the face of opposition from the left.

    Science and Technology are not Neutral

    Also, as opposed to running in fear from being labelled anti-vaxxers by a cheerleading corporate media, the left might at least consider the wisdom of foisting vaccines that have been granted under emergency use conditions on all age groups. Indeed, many on the left in Ireland seem unwilling to question dominant institutional narratives, a tendency recently criticized by the Greek socialist Panagiotis Sotiris in The Jacobin, who said: ‘What is missing here is something that used to be one of the main traits of the radical left, namely, an insistence that science and technology are not neutral.’

    It remains unclear whether universal immunization will bring about long-term ‘herd’ immunity; while in the absence of long-term safety data the benefits to young, healthy subjects of vaccination may not outweigh the cost in terms of adverse events from treatments granted under emergency use licences. Sober assessment seems to have given way to an ideological and, at times, a coercive approach.

    In terms of the efficacy of the Pfizer vaccine, writing in the British Medical Journal, Peter Doshi, pointed to how in the media ‘a relative risk reduction is being reported, not absolute risk reduction, which appears to be less than 1%’ for severe disease.’ Ollario et al in The Lancet referred to absolute risk reductions of ‘1·3% for the AstraZeneca–Oxford, 1·2% for the Moderna–NIH, 1·2% for the J&J, 0·93% for the Gamaleya, and 0·84% for the Pfizer–BioNTech vaccines.’ The authors also pointed to how ‘considerations on efficacy and effectiveness are based on studies measuring prevention of mild to moderate COVID-19 infection; they were not designed to conclude on prevention of hospitalisation, severe disease, or death, or on prevention of infection and transmission potential.’

    Doshi has also objected to the undermining of ‘the scientific integrity of the double-blinded clinical trial the company—and other companies—have been conducting, before statistically valid information can be gathered on how effectively the vaccines prevent hospitalizations, intensive care admissions or deaths.’  This came after Pfizer pleaded an ‘ethical responsibility’ to unblind its trial and offer those who received a placebo the opportunity to receive its vaccine.

    Doshi argued that ‘there was another way to make an unapproved vaccine available to those who need it without undermining a trial. It’s called “expanded access.” Expanded access enables any clinician to apply on behalf of their patient to the FDA for a drug or vaccine not yet approved. The FDA almost always approves it quickly.’

    An alternative policy would be to reserve vaccines for those most susceptible to severe symptoms – the old and the obese – along with healthcare workers and others unavoidably working around the world in congested environments. Devoting scarce resources to increasing ICU provision to bring us into line with European averages might be a better approach than relying exclusively on the quick fix of the vaccine.

    The Irish left should now desist from identity politics around vaccine uptake that the centre-right is relishing. ‘Tiktok’ Harris previously stoked tensions with talk of mandatory vaccines and promoting vaccine passports. The left should resist vaccine apartheid, nationally and globally, while demanding the release of patents earned through state supports.

    On the Horizon

    Ireland can expect significant social problems to emerge out of our world-beating lockdown strategy that recalls a prior devotion to austerity; a mental health pandemic and mass youth unemployment are upon us already. Moreover, the young are currently denied the safety valve of an easy hop to another English-speaking country for work. This may be a recipe for radicalism, but unfortunately genuinely dark forces on the far-right are ready to pounce on malcontents.

    It is surely vital that we maintain our European connections, thereby scrapping Mandatory Health Quarantine that is an insult to immigrant groups in Ireland, as well as the diaspora. 90% of scientists believe that Covid-19 will be with us forever, so it seems there will always be ‘variants of concern’ to contend with, just as there are with influenza.

    As a country Ireland has serious work to get on with in terms of addressing a housing crisis and improving our environment. A narrow focus on the pandemic should not be allowed to derail these efforts. This may be like a war but it is not a war. Even prior to vaccines, this is a virus with an infection fatality rate of less than 0.2% in most locations. Moreover, up to 86% of those infected may not have symptoms, such as cough, fever, or loss of taste or smell, according to a UK study from October. We require better provision of public health and an adequate plan to address the ongoing obesity pandemic.

    We also need to start thinking more critically — and speaking more cautiously — about Long Covid, considering ‘at least some people who identify themselves as having Long Covid appear never to have been infected with the SARS-CoV-2 virus.’

    We need to start thinking more critically — and speaking more cautiously — about long Covid

    A New Social Contract?

    The pandemic calls for a new social contract to be negotiated in Ireland that acknowledges republican values of Non-Domination; Mixed Government and tolerance of Obstreperous Citizens. The French COVID-19 Scientific Council led the way in a paper for The Lancet:

    it is time to abandon fear-based approaches based on seemingly haphazard stop-start generalised confinement as the main response to the pandemic; approaches which expect citizens to wait patiently until intensive care units are re-enforced, full vaccination is achieved, and herd immunity is reached.

    They continue:

    Crucially, the new approach should be based on a social contract that is clear and transparent, rooted in available data, and applied with precision to its range of generational targets. Under this social contract, younger generations could accept the constraint of prevention measures (eg, masks, physical distancing) on the condition that the older and more vulnerable groups adopt not only these measures, but also more specific steps (eg, voluntary self-isolation according to vulnerability criteria) to reduce their risk of infection. Measures to encourage adherence of vulnerable groups to specific measures must be promoted consistently and enforced fairly. Implementation of such an approach must be done sensitively and in conjunction with the deployment of vaccination across the various population targets, including all generations of society.

    They argue against reliance on lockdowns:

    Using stop-start general confinement as the main response to the COVID-19 pandemic is no longer feasible. Though attractive to many scientists, and a default measure for political leaders fearing legal liability for slow or indecisive national responses, its use must be revisited, only to be used as a last resort.

    To date, many on the Irish left appear to have had their heads in the sand promoting a Utopian ZeroCovid solution. This should give way to a more balanced appraisal that considers the interests of all of Irish society. With the youngest population in Europe, and as one of the richest countries, the Irish government could have preserved a far higher standard of living for the population during the pandemic. We now need to draw up a social contract that takes a more balanced approach.

    Featured Image: Daniele Idini

    [i] O’Toole, Fintan (editor), Up The Republic: Towards a New Ireland. Faber and Faber, London, 2012, p.1-52.

    [ii] Arendt, Hannah, The Origins of Totalitarianism, Penguin, London, 1966, p.22

    [iii] Eric Hobsbawm, How to Change the World, Tales of Marx and Marxism, Little, Brown, London, 2011, p.79

  • ‘Healthy People Do Not Require Genetic Vaccination’

    Editor’s Note: Having previously published Vaccination: A Matter of Trust with Caveats, we now anticipate objections from some readers to an article that may provoke vaccine hesitancy, at a point when rapid rollout to the entire adult population is widely touted as the only path out of interminable lockdowns. The author of this article, Dr. Marcus de Brun, however, is a medical doctor, and prior to his resignation last year– in protest against the government’s handling of the pandemic – a member of the Irish Medical Council. He also holds a first class degree in microbiology from TCD. Thus, we believe it is incumbent on Cassandra Voices as ‘a home for independent voices to inspire new thinking’ to provide this platform for him to articulate fully a public stance that he would not vaccinate a healthy person with any of the four vaccines currently on offer in Ireland. All the more so in a period of crisis, we maintain it is vital to give space to informed arguments that go against the grain. We invite comment and/or rebuttal, and ask if you appreciate this article that you offer a contribution to this publication, either through signing up with us on Patreon or through a single donation Buy Me A Coffee.

     

    Having recently stated publicly that I would ‘not administer a genetic-vaccine to a healthy animal, never mind a ‘healthy human being,’ I have been asked by friends (and foes) to clarify this statement, and will attempt to do so here.

    At present, vaccines produced by four companies (Pfizer, Moderna, Astra Zeneca and Johnson & Johnson) are available on the European market. All four are ‘genetic vaccines’ in that they are composed of synthetic DNA or RNA that is contained within a membrane or shell. In construction and appearance the vaccine is very similar to the SARS-CoV-2 virus responsible for the coronavirus disease known as Covid-19. The vaccine gains entry to human cells by a process that is almost identical to the manner by which a virus generally gains access to host cells. This process is called ‘transfection’.

    Each of these vaccines work by introducing either DNA or RNA into host cells. The genetic material then instructs host cells to make a piece of the coronavirus (the spike protein) that is then released into the blood stream or tissues. There, the spike protein will trigger an immune response. Following this immune response, the vaccinated individual will retain some immunity; they will have antibodies and white cells that can now recognise Covid-19 and attack it before it has a chance to cause a serious infection.

    The AstraZeneca and Johnson & Johnson vaccines are DNA vaccines,[i] which transfect DNA into the Nucleus of host cells. The Pfizer and Moderna Vaccines are RNA vaccines, these transfect their RNA into the cytoplasm of host cells. The difference will be explained later; however, the initial process is the same: human cells take up synthetic viral genes, those genes then direct those cells to begin manufacturing the spike-protein of Covid-19. The cells will then release the nascent spike-protein into the bloodstream or tissues, where it will then function as a ‘traditional vaccine.’

    In essence, the distinction between genetic-vaccines and ‘traditional vaccines’ is that the latter would involve a person being injected with killed or inactive virus or spike-protein, which would then cause our immune systems to mount a response. Each of these novel genetic-vaccines however, insert genetic material into human cells. These synthetic genes then ‘hijack’ those cells or ‘convert’ them to manufacture and release the spike-protein. With a genetic vaccine, pharma does not make the vaccine, our own cells are programmed to do the work instead, a process entirely different from that of a ‘traditional vaccine’.

    Out with the Old…

    For the first time in my medical career of some twenty years, I am presented with the apparent necessity of vaccinating young healthy people with experimental vaccines, against a disease for which they have little or no risk of suffering life-threatening,[ii] or even serious long-term[iii] illness. The vast majority of  ‘vulnerable’ people to whom they might pass Covid-19 have already been either vaccinated or been exposed to the virus.[iv]

    In Ireland according to our Central Statistics Office, during the past 12 months up to the end of January 2021; amongst the entire population of 1-24yr olds, there have been 55,565 PCR confirmed cases of Covid-19. Out of those cases, there has not been a single death recorded; from, by, or associated with Covid-19.[v] It has been reported that a single Covid-related death in this cohort (1-24yrs) did occur in February of this year. However, this has yet to appear in the figures published by the CSO.

    Young nurses, medical staff, care workers, are being pressured into taking a vaccine they probably don’t need themselves, despite residents under their care having been almost all vaccinated already. Now Covid-19 genetic-vaccines are being tested upon children as young as six months old.[vi]

    A Scarcity of Serious Questions? Or a Scarcity of Serious Media?

    The justification for many, if not most, policies during this crisis has largely been based on ‘mortality data’. In contrast, Swedish authorities have enforced relatively few restrictions, nor made masks mandatory. In Ireland, the CSO indicate that 92% of all Covid-related deaths have occurred in those over 65 years of age.[vii]

    In Sweden that cohort of their population is 3.17 times greater Ireland’s. Thus, if we roughly compare the Swedish mortality total (at the time of writing) of 13,262,  to the Irish total of 4588, and if we then multiply the Irish mortality total by 3.17, we arrive at a figure of 14,544, which is significantly higher than the comparable Swedish total.

    We are crudely, but reasonably, comparing ‘like with like’ to reveal glaring potential problems with our own relatively draconian Covid policies. When compared with Sweden, our own version of lockdown seems to have had no benefit in terms of preventing mortality. It might not be unreasonable to assert that our stricter policies may have contributed to a relatively higher mortality. Yet, perhaps the biggest question here is: why are there so few questions being posed in the media in respect of the efficacy of masks, lockdowns or vaccination policies?

    On the rare occasion questions are raised in our national media, it as if an ‘anti-vaxxer’, ‘right-wing loon’, or political extremist is trying to gate crash what might otherwise be a rather sedate and respectable party.

    Pro-Vaxxer

    In the good old days before Covid, in Ireland, and around the world, we only vaccinated those who were vulnerable to, or at risk from a specific disease. We still vaccinate children against an array of illnesses that adults have not been, and are not routinely vaccinated against; Rotavirus and Meningitis B are but two obvious examples. Adults are equally susceptible to infection by either, but they are not as vulnerable to serious illness, and so are not vaccinated. Previously, we only ever vaccinated the vulnerable and those at risk; recently, however, that good science and common sense has been turned on its head.

    It is suggested that we should vaccinate young healthy people who have little if anything to fear from Covid-19. A paediatric genetic-vaccine is expected to be available later this year. It is argued that even though children are generally not susceptible to serious disease, they should be vaccinated in order to protect the vulnerable and achieve ‘herd-immunity.’ In the meantime, the vulnerable have in large part already been either been vaccinated already, exposed or sadly passed away.

    In a recent post on Twitter Michael Levitt, Nobel Laureate and Professor of Biophysics at Stanford University said:

    If getting the disease does not give immunity, how do you think that a vaccine that makes the same spike protein as the virus makes will give immunity?

    It beggars belief that with over a quarter of a million cases of Covid-19 already confirmed in Ireland, [viii] those who have already contracted the virus, are not at least being offered antibody testing prior to being offered (or pressured into taking) a new type of vaccine; novel vaccine that have recognised associated risks, and have not completed all safety trials.

    Between March and June, 2020, 96% of additional deaths related to COVID-19 in Europe occurred in patients aged older than 70 years [ix] We have clearly lost sight of whom we are trying to protect, and what we are trying to protect them from. Presently we have a national obsession with conformity, and an ostensible adherence to guidelines. Despite empirical truths, and substantial contrary evidence, we are being corralled into what increasingly appears to be a specific belief-system surrounding Covid-19, and its threat to the entire population.

    Those who have read George Orwell’s Animal Farm (1945) will be familiar with the threats issued to the hapless animals: ‘Jones the farmer will return, and destroy all of your good work!’ In contemporary parlance, he will return with ‘Long Covid,’[x] and frightening ‘New Variants’ with him.

    https://twitter.com/bergerbell/status/1379143927542947841

    Politicians have applied policies that are in keeping with this notion of ‘universal severity’ in response to a virus where 86% of those infected did not have virus symptoms, such as cough, fever, and loss of taste or smell., according to a UK study from October.[xi] Many of our Covid policies arrive with the benefit of preserving established governments from demonstrations and assemblies calling for policy revisions and or enquiries.

    My own calls for a public enquiry into nursing home deaths, or my pleas on behalf of common sense and natural science, are at best ignored by media. As are those of colleagues who feel and believe as I do, including Limerick GP Dr. Pat Morrissey, and Wexford GP Dr Gerry Waters, who was recently suspended by the Medical Council for refusing to adhere to and promote current public health guidance. Others who have openly spoken out against current policies have been subjected to investigation by the Medical Council, and ongoing vilification by many of our peers. Speaking out returns precious few short term dividends.

    Throughout much of Europe since the outset of the crisis, governments, like our own, are presently controlled by proxy scientific-panels or unelected expert committees. Governments claim to be simply ‘following their scientists advice,’ whilst the scientists insist that they are merely informing the government and not directing government policy. In this apparently blameless political ‘no man’s land’, the stage is perfectly set for blameless political atrocities.

    War of the Words: ‘Genetic vs ‘Traditional’

    Many scientists and physicians prefer to describe most Covid-19 vaccines as ‘gene therapy’. It is a phrase that no doubt serves as much to antagonise proponents, as it does to inform them. However, it is as good a place as anywhere to start.

    Genetic vaccines are certainly not ‘traditional’ vaccines. The licence for their use against Covid-19 throughout Europe was granted under emergency legislation that permits manufacturers to skip phase 4 safety trials that would have otherwise delayed their distribution. Advocates insist that skipping this final phase was absolutely necessary to resolve the current crisis.

    There is much to this argument, and we will not dive into it here. However, one point should be made. There are at least two off-patent (cheap and safe) drugs, Hydroxychloroquine and Ivermectin, that may be effective in treating Covid-19. These drugs are not, however, licensed for use in treating Covid in many Western countries, (particularly the wealthier ones who can afford the novel vaccines).

    https://twitter.com/EvidenceLimited/status/1379400534000594945

    If either, or both, drugs had been licensed, this might have proved an obstacle to the granting of emergency use licences for Covid-19 vaccines. The reason for this is that grounds for emergency licensing of genetic-vaccines are substantially reinforced, as long as there are no other pharmacological treatments available at the time.

    Edward Jenner (1749-1823)

    A Traditional ‘Vaccine’

    In China the practice of inoculation against diseases such as smallpox was established as far back as 200 BC.[xii] It is likely that traditional medicine, tribesmen and ancient civilisations used, or at least inadvertently ‘knew’ something of the benefits of limited exposure to a disease, in order to establish some degree of immunity.

    Our own modern era of the ‘traditional’ vaccine begins when Edward Jenner (1749-1823) noticed that milkmaids appeared to be relatively immune to smallpox, a viral illness that was, in Jenner’s day, responsible for widespread suffering and death.

    Jenner observed that something was being transmitted from the cows to the milkmaids, effectively protecting them against smallpox. Cows contract cowpox. It’s not the same disease as smallpox, but as the respective viruses are so similar, whenever the hands of a milkmaid came into contact with a blister or pox on the udder of a cow infected with cow-pox; the milkmaid would be exposed to this very similar virus.

    In these instances the cowpox virus or ‘pieces’ of it, would enter the milkmaid’s blood stream through a cut or minor abrasion on her hands. The virus would be identified by her immune system as a ‘pathogen’ or disease-causing agent. White cells would attack the cowpox virus, causing it to break apart. Those same white cells would manufacture antibodies; little Y-shaped proteins that will stick to surface-proteins on the virus, and cause it to be directly destroyed, or recognised by other white cells that will mobilise to destroy it.

    All of this complex immunology would of course be occurring within the milkmaid’s blood, whilst she happily milked her cows. She might notice a slight blister, a little pus, or minor swelling around one of the abrasions on her overworked hands. The slight redness might be ignored, and would inevitably fade away. However this localised reaction would have heralded exposure to cowpox. The cowpox antibodies would then persist in her blood, remaining attached to the surface of many of her circulating white blood cells; protecting her or “vaccinating” her against small-pox.

    If the milkmaid should later come into contact with smallpox, those newly formed cowpox antibodies would be ready to mount an early and more efficient immune response. Her antibodies to the cowpox virus could attach to the smallpox virus, recruit other white cells – killer t-cells etc – onto the scene, and mount a pre-emptive response. This would be fast enough to eradicate the smallpox infection before it had an opportunity to spread and cause severe illness or death. It was Jenner’s genius that ultimately brought this reality to light.

    Jenner collected some of the pus that oozed from the udders of cows infected with cowpox. He swirled it about in a drop of water, placed it in a glass vial and then offered it to the world as the prevention for small-pox. Half a century later Louis Pasteur coined the phrase ‘vaccination’ after vacca, the Latin for cow. The paradigm in respect of human medicine and public health had shifted forever.

    Louis Pasteur.

    Perhaps the real hero of the vaccination story was an eight-year-old boy by the name of James Phipps, the son of Jenner’s gardener. On May 14th 1796, Jenner made a small incision into James’s arm, and rubbed in a drop of his magical ‘pus-paste’, making little James the first to be given a vaccine in the modern sense.

    Thankfully, little James proved immune to the various small-pox ‘exposures’ and challenges that Jenner then came up with. At the time small-pox was responsible for almost 10% of annual deaths in England. Jenner sent his results in a paper to the Royal Society for publication, but his paper was ignored.

    Having had the audacity to suggest pus from an infected cow’s udder, as a cure for smallpox, Jenner was at first dismissed as an eccentric by his peers. Yet, rather than disappearing into obscurity, he persisted. He vaccinated a further twenty-three people, and having seen little James survive, he even included his own eleven-month old son Robert, in this first ever vaccine trial.

    At that stage the medical establishment found it impossible to ignore his findings, which soon attracted widespread interest amongst the medical fraternity. However, it was not until 1840, some forty-four-years after his first attempt to publish his results, that the British Government began offering Jenner’s vaccination, free of charge, to the general public.

    The same but different

    Since Jenner’s day, ‘traditional vaccines’ have functioned in precisely the same way. Pharmaceutical companies take a virus or bacterium, they break it up, kill it, or leave it intact but render it weaker or ineffective ‘the same but different.’ They then take the bug (or pieces of the bug), swish them around in a little drop of water, add in a few elements that act as preservatives and immune-stimulants; then we doctors inject those pieces into people, thereby preventing many from succumbing to various infective diseases. The vaccination exposes us to a bug or pieces of a bug causing our immune system to generate antibodies and white blood cells that will persist in our circulation and be ready to launch a pre-emptive strike against the bug or a similar bug if it is encountered again: we have, in essence, become immune.

    So what is different about genetic-vaccines? Well here’s where the story becomes a little nuanced. Let’s try to put it in terms we might relate to.

    To begin with we must remind ourselves that: all living things are composed of cells, which is perhaps the most basic tenet of biology.

    Image of a recreated 1918 influenza virus.

    Viruses are not considered ‘living things’, because they are not ‘cells’ and neither are they made up of cells. They are formally referred to as ‘obligate intracellular parasites.’ They only become ‘alive;’ and can only replicate, after entering host cells, at which point they replicate or multiply within host cells. Once inside a cell the virus hijacks the cell’s own processes for making things that the cell needs for itself. The infected cell then becomes a virus factory, it swells with new virus particles, until it bursts, dies, and releases its payload of new virions into the bloodstream, or fluid outside of the cell membrane.

    It is only when a virus is outside the cell, within the blood stream or tissues, that it might be recognised by white cells or antibodies, and become the subject of an immune response. When a virus is inside one of our cells, there are some discrete ways this cell can let other cells know that it has become infected; there are means by which the immune system detects that one of our own cells has a virus inside it. However, these are comparatively slow, indefinite and uncertain processes and will not be discussed here. The major and most important way the immune system clears viruses is by getting at them before they get inside our cells.

    Once a virus is inside a cell, for the most part, it is hidden from the immune system. This point will be crucial to understanding the distinction between a genetic vaccine, and a traditional vaccine.

    All Cells Look a Little, or a Lot, Like a Fried Egg:

    Under a microscope, all cells appear a little like fried eggs. Almost all of them have the same basic plan, the yellow yolk being the nucleus; the white of the egg, the ‘cytoplasm;’ and the outer margin of the fried egg (the crispy brown edge) being the ‘cell membrane’ or wall surrounding the cell. To learn the basics of how genetic vaccines work, we need only refer to this analogy, but we must understand our ‘egg’ a little better before we put the toast on.

    The yellow yolk, or nucleus, contains all of our DNA. To understand what DNA looks like, imagine your fly, not the one buzzing at the window, but the zip on your trousers. It is composed of two sides or strands that are linked together when your zipper is up, and separated when your zipper is down.

    DNA is like an extremely long length of closed zip. Imagine this super long ‘zip’ coiled into individual space-saving packages, like neat balls of wool. Each of these little packages is called a chromosome and (with the exception of sperm cells and egg cells) the nucleus of each of our cells contains forty-six of these little balls of wool; twenty-three from mum, and twenty-three from dad.

    All forty-six are packed into the nucleus, the yellow yolk of our analogous egg. When we, or one of our cells, needs something; a protein, a hormone, a replacement part etc., the information to make what the cell needs (the recipe for all of life’s necessities) is coded for in that length of closed zip, our DNA.

    Each of the ‘teeth’ along the length of the zip strands, represent a single letter of the genetic code. An entire message may contain many letters, or teeth, along a specific length or piece of the zip. The lengths of zip that contain messages (or recipes) are called our ‘genes.’

    The ‘message’ within a gene is like a recipe in a cookbook. It contains a coded instruction for how to make the protein, enzyme etc., or whatever it is that the cell wants or needs. The DNA code is in the nucleus, and the basic ingredients are located in the cytoplasm, and it is in the cytoplasm (the egg-white) where the item required is assembled and manufactured. The raw materials for manufacture get into the cytoplasm, when they are absorbed across the cell membrane (the crispy brown bit at the edge of our fried egg). These raw materials are the amino-acids, sugars and vitamins etc., that we receive in our diet.

    To kick off the process, when a cell needs to make something, a signal is sent from the white of the egg (the cytoplasm) into the nucleus. That signal makes its way to the ball of wool or chromosome that contains the particular recipe, or code for the ingredients that will make up whatever is needed by the cell. When the signal reaches the chromosome containing the particular recipe or gene, the ball of wool is loosened slightly, and a relatively small length of closed zip (or DNA containing that recipe), is unzipped. One side of the opened zip is then copied into a piece of mRNA.

    That copy of one side of the unzipped zip is called messenger RNA. In most textbooks it (the mRNA) looks exactly as I have described it: a single side of a zip. This messenger RNA then exits through pores in the nucleus.  It enters the white of the egg, where this mRNA ‘recipe’ is then read or translated, and whatever it is the cell needs can now be manufactured within the cytoplasm or the white of the egg.

    The Ribosome

    When the strand of messenger RNA leaves the nucleus and enters the cytoplasm it is immediately found by a fascinating little cytoplasmic protein called a ‘ribosome’. The ribosome attaches to the mRNA. It then slides along this single strand of zip, and as it does so, ‘reads’ the code, and then makes a little strand, like a bead of pearls (a polypeptide). That strand of polypeptide then curls and folds itself into a little ball or blob; and this little blob of protein, is the very thing that the cell was looking for in the first place.

    It might be a structural protein, an enzyme, a building block, a replacement part, or whatever. When the ribosome slides along the piece of mRNA it makes this new little string that will ultimately fold upon itself to become the required product. This wonderful orchestral process is as ancient as life itself and is called ‘translation.’

    It is one of the rare occasions when jargon makes sense, for the little piece of mRNA, has indeed been ‘translated’ into a protein or ‘final product’ by the ribosome. The cell has now manufactured the thing that it needs, and after a few translations, the mRNA then degrades. No more ribosomes can attach to it, and no further product can be manufactured from it. If the cell wants another product it must send another message into the nucleus and call for another mRNA copy to be made in the nucleus and sent into the cytoplasm. It is a beautifully organised process, integral not simply to human life but to all life on the planet.

    How Does a Genetic-Vaccine Work?

    If you got all of that, you have grasped some of the fundamentals of cell biology and we are now able to ask: how does a genetic vaccine work?

    Most of us have seen an image or an artist’s impression of what a coronavirus looks like. A little ball, covered in spikes, like a medieval weapon swung from the end of a chain. Inside this little ball are the virus’s own genes. These genes are in the form of strands of RNA; the same type of RNA that is made in the nucleus of our cells, and sent into the cytoplasm for the manufacture of all ‘things’ that the cell needs.

    SARS-CoV-2

    The main difference between the RNA strands within a coronavirus, and those that naturally emerge from the nucleus of our own cells, is that coronavirus RNA does not code for ‘things’ that our cells might need. On the contrary, it codes for pieces that make up the coronavirus itself.

    When a coronavirus binds to the outside of one of the cells in our respiratory tract, it releases its RNA into those cells – into the white of the egg – and there, instead of making proteins that are needed by our cells, our ribosomes attach to their viral RNA and begin to manufacture (or translate) proteins that make up the physical structure of the virus. The host cell has now becomes a virus-making factory; the cytoplasm swells with viral particles; the cell bursts, and thousands of new viruses (virions) are released into the bloodstream, or the fluid that lies outside of the cell membrane.

    A genetic vaccine looks like, and functions, in almost exactly the same manner as the coronavirus itself. If a genetic vaccine could be visualised, it would look like a little sphere that encapsulates a piece of viral RNA or DNA (depending on which of the four vaccines we are considering). The role of the sphere is to protect the RNA or DNA inside the vaccine, and, most importantly, to bind it to human cells in a manner that will allow the piece of RNA or DNA to enter host cells at the site where the ‘vaccine’ is injected.

    For an RNA containing vaccine (Pfizer & Moderna) once the vaccine RNA gets inside our cells, our ribosomes attach and translate the RNA into a piece of the virus (one of the spike proteins). The host cell will then swell with spike proteins, and release them into the blood stream or body fluids outside the cell. There, the spike-protein will trigger the same immune response that Jenner and the traditional vaccines make use of.

    For DNA vaccines (Johnson & Johnson, AstraZeneca) the vaccine-DNA makes its way into the nucleus of our cells where it begins working (and is treated the same as our own DNA). It is copied into a piece of mRNA that will then travel into the cytoplasm and be translated by ribosomes into spike-proteins. Because genetic vaccines cannot infect cells, the process whereby a genetic-vaccine enters host cells is referred to as ‘transfection’.

    It is only after the transfected host cell releases spike-protein into the blood stream that our genetic-vaccine begins working in the ‘traditional’ way. In reality, it is the cellular process for the manufacture of things which has been hijacked, and the ‘traditional vaccine’ is being made inside one’s own cells. The ‘vaccine’ is released into our blood stream in the same way that a cell infected with a virus releases new virus into the blood stream or tissues.

    The final result might be the same, however, where a genetic-vaccine is different is in its mechanism it operates inside cells at a level of intimacy that Jenner could never have imagined. Because DNA vaccines enter the nucleus of our cells, and are treated as our own DNA, they come with a risk of damaging our own DNA, causing mutations, including, potentially, cancer. The potential is indeed an established fact. It is no less established than the fact that there is a link between smoking and cancer.

    Consider when a piece of synthetic DNA comes within intimate proximity of a relatively enormous coiled ball of DNA that is dynamically unwinding and unravelling in response to the daily activities of the cell. Is there a chance that this relatively small piece of synthetic DNA might become incorporated into or interfere with the normal function of our own DNA? Before Covid, the answer was an emphatic yes. However of late, the mere suggestion will undoubtedly be treated as something of a ‘conspiracy theory’.

    It is for this and other reasons that genetic-vaccines have not been previously licensed for use in humans prior to the current crisis. Thus, a 2013 paper[xiii] published in Germs, the respected Journal of Infectious Diseases lists the established disadvantages of DNA vaccines.

    Crossing the Rubicon

    At this point the reason critics refer to current Covid-19 vaccines as ‘gene therapy’ should not be too difficult to understand. It is important to bear in mind that as the cellular process of translation can be hijacked to produce a ‘vaccine’, it can also be hijacked to produce a myriad of other potential pharmaceutical therapies.

    Very limited forms of gene therapy are available in the treatment of terminal cancers. However, pharmaceutical companies have not been able to market this form of medicine, outside of the laboratory, on human populations.[xiv] A cynic might reasonably argue that companies are exploiting the current crisis in order to expedite safety trials and open the market for ‘gene-therapy’.

    There is nothing new here, this type of therapy, whereby patients are administered the gene for a missing or desired product, has been in development for several decades. The major difficulty for pharmaceutical companies has been how to get it out of the laboratory and past the paralysis of safety trials. It is certainly easy to see that if our cells are programmed to make and release spike-proteins, they can also be programmed to release other kinds of proteins, drugs and potential therapies directly into the human blood stream or tissues.[xv] Getting this type of therapy past regulators, and avoiding meaningful debate, has, (for better or worse), clearly been accomplished within the context of the current crisis.

    From a simple economic perspective, if human cells can be programmed to take on the role of manufacturing the ‘drug’, numerous difficulties in respect of production, costs, delivery, and even safety trials, are relatively easily overcome. The paradigm shift that resulted from Jenner’s development of vaccination could pale into insignificance compared to the potential game changer of genetic-vaccine.

    Ah go on. You’ll be grand!

    If, indeed, these vaccines are going to protect people from Covid-19, and they come with the added benefit of paving the way for novel therapies, why are people like me getting our proverbial knickers in a twist?

    Again the answer is not that complicated. The cellular process of ‘translation’ that is being ‘hijacked’ by the relevant pharmaceutical companies, does not belong to them, to our respiratory cells, or even human cells. As mentioned already, it is a process that belongs to ALL cells, in ALL species. In essence it ‘belongs’ to all living things in Nature.

    If anything happens to go wrong, the consequences are not limited to human beings, as the process being ‘hijacked’ is not exclusive to us. It ‘belongs’ to all life on Earth. The consequence of error, may extend further than a little nausea or swelling at the injection site.[xvi] Potential consequences extend to all cells that utilize the same process, and come in contact with the manufactured DNA or RNA.

    DNA or RNA? Red or White?

    Whilst the potential for either of the two available DNA vaccines to integrate into, or damage, human DNA is well established; there is an argument being made that this cannot possibly occur with the two available RNA vaccines.

    Generally speaking within our cells once RNA is copied or made in the nucleus it moves into the cytoplasm. It does not travel backwards. RNA does not move back inside the nucleus and incorporate into our DNA. However, the key words here are: ‘generally speaking.’

    Nature (generally speaking) blocks this possibility because the copied RNA that exits the nucleus, is different to DNA. It is an RNA copy of the DNA, the RNA cannot bind or interact with DNA. In the first instance RNA is a single stranded copy of one side of the zip. In the second instance the ‘teeth’ on the newly copied RNA are slightly different. They are tweaked with a sugar molecule called ribose, they are ‘ribosylated’ and therefore cannot readily recombine with DNA. (The ‘R’ in RNA simply means Ribosylated Nucleic Acid.)

    The RNA does indeed code for the same message that is contained within the DNA, but the teeth, or the letters of the RNA code, are slightly different. RNA does not travel backwards and interfere with DNA. Generally speaking they are incompatible, and cannot interfere with each other. Therefore, when the vaccine makers insist that the pieces of RNA that they have transfected into our cells do not interact with our DNA; well, they aren’t spoofing. It doesn’t normally happen that RNA interferes with DNA.

    So that’s what it says on the tin. However, there are two points that must be considered before we take this claim at face value. The first is a question of ‘precedence’ and the second is a question of scale.

    Does it happen in humans and in Nature that RNA can travel backwards into the nucleus and interfere with or incorporate into DNA? The simple answer to this question is a definite yes! RNA can and does travel backwards to incorporate itself into our DNA. This retrograde move, (where RNA sequences become incorporated into DNA) is called reverse-transcription. The reason for the use of ‘retro’ in the word retrovirus, is because retroviruses, and many other viruses, make use of reverse-transcription, converting RNA into DNA that will then integrate into our own DNA.

    HIV and HTLV (a human virus that causes t-cell leukaemia) are examples of viral infections, where RNA is converted backwards into DNA which then ‘interferes’ with our own DNA inside the nucleus of our cells. These viruses contain RNA, and they also carry an enzyme called ‘reverse transcriptase’. This enzyme converts RNA backwards into DNA. Retroviruses and other viruses (such as Hepatitis B) introduce the reverse-transcriptase enzyme into our cells when they infect them.[xvii] Furthermore, our own cells normally produce and use this enzyme (reverse transcriptase) inside the nucleus, where it has some ‘house-keeping’ roles in maintaining our own DNA.[xviii]

    Perhaps even more interesting is the fact that within the human genome some 8% of our DNA is composed of DNA that was originally viral RNA. Infections with RNA viruses whose genes have since become permanently incorporated into our own DNA. These sequences are called ‘Human Endogenous Retroviral Sequences’ or HERVS.[xix] Many of them persist within our genome because they may code for proteins or things that are likely to be of some benefit to us; genes brought into our genome from outside the cell, via the natural, dynamic interaction between viruses, retroviruses and human DNA.

    Many more of these endogenous retroviral (originally RNA) sequences are mysteriously redundant, and science is yet to learn of their function in sickness or in health. The fact remains that they are present; been present for countless millennia; may be integral to our evolution as a species; and are certainly with us ‘until death do us part.’ They should serve to remind us that there is a long established history of communication between viral and human genetics; an interaction that we should attempt to understand before it is blindly manipulated.

    Interconnectedness

    Too often viruses are portrayed as static structures, distinct from our own genetic material and distinct from one another. This is quite simply a rather primitive concept, the same kind of thinking that removes human beings and the consequence of our actions from Nature. It is part of the reason we remain largely incapable of seeing and appreciating the vast web of interconnectedness that dependently joins us to whales, rain forests, and even viruses.

    We depend upon viruses for our genetics, as we depend upon yeast for our beer. Often viruses depend upon each other to cause infection. In certain instances, if a particular virus is missing something, a part or component (without which it is defective or deficient), the missing part is supplied by another helper-virus. There are helper-viruses, and there is an entire family of viruses (dependoviruses) that are entirely dependent upon assistance from helper-viruses. For example, in Humans, Hepatitis D virus is activated, only in the presence of Hepatitis B virus. Essentially, in order to function, the D-virus ‘borrows’ some missing parts from the B virus.

    In short, viruses are not ‘monogamous recluses’: interacting with each other; helping each other; interacting with our genetic material within the cytoplasm and within the nucleus. It does not matters if that genetic material has come from the nucleus of our own cells, or been synthesized in the labs at Johnson and Johnson.[xx]

    A Question of Scale

    There is no such thing as a ‘perfect process’. Do something for the first time and you might do it right,  do it right enough times, and you will eventually do it wrong. 

    When vaccine RNA or DNA hijacks a natural cellular processes and transforms the cell to vaccine or spike-protein production; how many times does this ‘event’ occur in the tissue of the person who has thus been vaccinated? Thousands, or several thousands of times? How many times has it occurred when several billion people are vaccinated? I don’t know the answer to this question. However, when a process is repeated billions of times, mistakes are no longer ‘possible’, they are inevitable. Such mistakes or mutations are not only inevitable but are essential, lying at the heart of evolution itself.

    The End is Nigh?

    There is certainly a mountain of spin and delusion on either side of the ‘genetic-vaccine’ or ‘gene-therapy’ debate, and we must keep matters in perspective. Genetic modification is here to stay, for better or for worse. The argument in respect of unforeseen genetic consequence to ourselves and/or other species is an old one. It began with ‘Dolly’ the sheep, and has raged for some time around the desirability of genetically modified foods.

    Ironically, the introduction of synthetic genes into vegetables, created something of an international furore, yet the transfection of synthetic genes into millions of regular human beings has created far less controversy. Debate or discussion on the subject of genetic modification or therapy, its necessity, utility, or potential harm, is long overdue; although perhaps it might be a case of too little, too late.

    Today, many of the foods we eat have been genetically modified to some degree. Genetically modified food is, however, met with and processed by the acid and digestive enzymes in our guts. The synthetic genes in GM products do not (as far as we know) enter our cells, they do not attempt to manipulate our own cellular or genetic processes.

    There is clearly an urgent need to revisit this debate in light of these new vaccines. The battle may have been lost in respect of GM crops, but there is a reasonable argument to be advanced this time round as ‘human genetic processes’ are being tampered with, rather than sheep, beetroot or soya beans.

    The Right Hashtag?

    In recent years discourse and protest have become strangely predictable, organised around or stimulated by whatever happens to be trending on social media. It seems the right hashtag hasn’t been developed for ‘debate’ in respect of current pandemic policy, even as that policy extends into the function of our own cells.

    How many people in Ireland, or around the world, know how a Covid vaccine work? How many clinicians are aware for that matter? When debate does erupt in relatively small pockets around the country it is hijacked by extremists or dismissed as being organised and attended by extremists. Social media appears to be moderating our behaviour to a greater degree than even genetics.

    The health of our society depends far more on constructing a more honest and happier version of ourselves. We need to re-evaluate materialism, define happiness, reduce consumption, eat less (or no) meat, take plastics out of our food chain and ecosystems, restore and preserve habitats, protect and understand a biodiversity upon which we are entirely dependent. All of this, and more, is not contingent on genetic modification, no more than it is dependent on us getting to Mars.

    Therefore, for the reasons I have outlined, I would not inject a healthy animal with an experimental genetic-vaccine, never mind a healthy human being.

    [i] Jonathan Corum and Carl Zimmer, ‘How the Oxford-AstraZeneca Vaccine Works,’ New York Times, March 22nd, 2020,  https://www.nytimes.com/interactive/2020/health/oxford-astrazeneca-covid-19-vaccine.html

    [ii] Smriti Mallapaty, ‘The coronavirus is most deadly if you are older and male — new data reveal the risks’ August 28th, 2020, https://www.nature.com/articles/d41586-020-02483-2

    [iii] Adam W. Gaffney, ‘We need to start thinking more critically — and speaking more cautiously — about long Covid’ Statnews, March 22nd, 2021, https://www.statnews.com/2021/03/22/we-need-to-start-thinking-more-critically-speaking-cautiously-long-covid/

    [iv] Conor Pope, Vivienne Clarke, ‘Vaccination rollout in nursing homes almost complete, HSE says,’ February 12th, 2020, Irish Times, https://www.irishtimes.com/news/health/vaccination-rollout-in-nursing-homes-almost-complete-hse-says-1.4483250

    [v] CSO. https://www.cso.ie/en/releasesandpublications/ep/p-covid19/covid-                                                19informationhub/health/covid-19deathsandcasesstatistics/

    [vi] Moderna Announces First Participants Dosed in Phase 2/3 Study of COVID-19 Vaccine Candidate in Pediatric Population https://investors.modernatx.com/news-releases/news-release-details/moderna-announces-first-participants-dosed-phase-23-study-0

    [vii] CSO. https://www.cso.ie/en/releasesandpublications/ep/p-covid19/covid-                                                19informationhub/health/covid-19deathsandcasesstatistics/

    [viii] https://www.google.com/search?client=firefox-b-d&q=covid+deaths+ireland

    [ix] ‘Immune evasion means we need a new COVID-19 social contract’, The Lancet, February 18th, 2021, https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(21)00036-0/fulltext

    [x] Jeremy Divine, ‘The Dubious Origins of Long Covid’, Wall Street Journal, March 22nd, 2021,  https://www.wsj.com/articles/the-dubious-origins-of-long-covid-11616452583

    [xi] Angela Betsaida B. Laguipo, ‘86 percent of the UK’s COVID-19 patients have no symptoms,’ News Medical Life Sciences, October 9th, 2020, https://www.news-medical.net/news/20201009/86-percent-of-the-UKs-COVID-19-patients-have-no-symptoms.aspx

    [xii] The History of Vaccines, Chinese Smallpox Inoculation, https://www.historyofvaccines.org/content/early-chinese-inoculation

    [xiii] Germs. 2013 Mar; 3(1): 26–35. Published online 2013 Mar 1. doi: 10.11599/germs.2013.1034/

    [xiv] Kristina Fiore, ‘Want to Know More About mRNA Before Your COVID Jab?’ Medpage Today, December 3rd, 2020, https://www.medpagetoday.com/infectiousdisease/covid19/89998

    [xv] Nature Reviews Drug Discovery volume 17, pages261–279(2018)

    [xvi] Nicola Davis, ‘Covid vaccine side-effects: what are they, who gets them and why?’ The Guardian, March 18th, 2021, https://www.theguardian.com/world/2021/mar/18/covid-vaccine-side-effects-what-are-they-who-gets-them-and-why

    [xvii] Medical Microbiology. 4th edition (Chapter 62).Galveston (TX): University of Texas Medical Branch at Galveston; 1996.

    [xviii] Proc Natl Acad Sci U S A. 1986 Apr; 83(8): 2531–2535.
    doi: 10.1073/pnas.83.8.2531, https://www.nature.com/articles/1205081

    [xix] PMCID: PMC7139688 PMID: 32155827 Human Endogenous Retroviruses (HERVs): Shaping the Innate Immune Response in Cancers.

    [xx] Knipe, David M.; Howley, Peter M. (2007). Fields Virology (5th ed.). Lippincott Williams & Wilkins. pp. 126–7.

     

     

  • I Do Not Consent

    I didn’t particularly want to write this article.  I didn’t want to get involved in the whole online social media circus of opinion and rebuttal, triggering and offense. But I feel like I have something to say, and what I have to say is important. So I’ll speak my truth.

    About a month ago, I completely removed my attention from the hysterical world of 24-hour news cycles, social media, the conspiracy theories, the craziness, the arguments and rebuttals, the fear, projection and lashing out. So I stopped watching the news and left Facebook, and very liberating it was too.

    The collective process the world was going through as a result of Covid-19 (Coronavirus) was taking its toll on me. I had never experienced such fear and anger online before. People were literally lashing out, blurting their unprocessed emotions, fear and anger, all over social media, mirroring perhaps, conversations that were occurring in family homes all around the world.

    Instead, I put my energy into the world around me: learning new skills, fishing, growing food, renovating a cottage. Putting my energy and vision into creating a new reality. But something is making me speak out at this time.

    I would like to preface what I am saying by acknowledging that Covid-19 is a real threat that has caused great loss and suffering to many families all around the world.

    The collective hysteria resulting from it, however, is every bit as damaging as the virus itself.

    On the nature of fear

    My background is as an outdoor guide. I spent two decades guiding in remote and sometimes dangerous rivers and mountains on four continents. During that time I became very familiar with the nature of fear. A large part of the psychological aspect of guiding in adventurous environments involves managing people’s fears.

    Solo seakayaking around Ireland, 2014.

    One lesson I learnt beyond any doubt is that fear is contagious. Just like a virus. If one person in a group becomes fearful, it spreads like wildfire throughout the entire group, a legacy of our evolutionary heritage, and the fight or flight mechanism.

    What we have witnessed, in the past few months, is the entire human species in fight, flight or freeze mode. It is collective anxiety on a global scale, amplified by social media and hysterical media coverage.

    Our political leaders, for the most part doing their best and responding to an unprecedented situation, were pressured by a fearful media and hysterical public to do something, anything, and naturally they reacted from a place of fear.

    As anyone with a background in adventure sports will know, good decisions are never, ever made from a place of great fear or hysteria.

    The Indian philosopher Krishnamurti wrote: ‘Fear of any kind breeds illusion … where there is fear there is obviously no freedom … It makes one tell lies, it corrupts one in various ways, it makes the mind empty, shallow.’

    I am not suggesting that our government in Ireland is consciously part of some nefarious plot to undermine democracy. Not intentionally anyway. But democracy has nevertheless been undermined as a result of the hysterical response to Covid-19.

    In the UK, former Supreme Court Justice Jonathan Sumption said: ‘This is what a police state is like, it is a state in which a government can issue orders or express preferences with no legal authority and the police will enforce ministers’ wishes’. He has called the lockdown ‘the greatest interference with personal liberty in our history’. When great legal minds are telling us that the rule of law is being undermined, we should listen.

    Our civil liberties and civil rights are not something that we be taken for granted. We forget now that Irish independence and the fight for freedom came at a high cost. ‘The price of liberty is eternal vigilance’, is a quote attributed to Thomas Jefferson.

    It does not matter whether you consider yourself to be politically on the left, centre, or the right, the erosion of civil liberties that has occurred in most Western democracies over the last few months is something that should concern you. if the there is one thing the history of the last century has taught us, it is that tyranny can take many forms.

    Image: Daniele Idini (c)

    You may well have great trust in our current government. That is not the point. The point is that future governments may well use the same arguments to repress civil liberties. Consider the possibility of a less benign government with opposing political views to your own coming into power in the future, and using the precedents set at this time to undermine your civil liberties. We do not have to look far back in history to see that such events are very possible. Once a precedent is established, it is an easy path to follow.

    Over two thousand years ago, Plato warned of the dangers of tyranny arising from a fearful and chaotic democracy. The people, when afraid, beg for a strong leader to come to save them. Tyranny can arise, not from a despot seizing power, but through a fearful public demanding protection from an external threat. This threat is real, but is overblown: ‘This and no other is the root from which a tyrant springs; when he first appears he is a protector.’

    Many other great political thinkers have expounded on the idea of the tyranny of the masses. The great Irish political theorist Edmund Burke, wrote in a 1790 letter that ‘The tyranny of a multitude is a multiplied tyranny’.

    John Stuart Mill in his famous essay ‘On Liberty’ (1859) spoke of the need to protect against, ‘the tyranny of the prevailing opinion and feeling … as the majority opinion may not be the correct opinion.’

    We confront a dystopian nightmare of an Orwellian society of constant surveillance, with the government and/or corporations controlling what we can think, what we say, and how we act.

    Militaristic language has become all too commonplace, thereby justifying extreme wartime measures. We talk of ‘front line’ workers. Much as these amazing doctors and nurses are doing a wonderful job and should be commended, there is no ‘front line’.

    This is not a war. You cannot fight a war against a part of Nature. That is like fighting a war against yourself, a mass collective schizophrenia. This is part of the problem with our current rational-materialistic society: in our arrogance we believe ourselves to be somehow separate from Nature. This crisis is showing us clearly that we are not.

    The following liberties have been undermined since the start of the Covid-19 hysteria:

    1. The right to personal liberty and to protest. 

    Article 40.4 of the Irish constitution guarantees a right to liberty, while Article 40.6.1 says you have a right to assemble and to associate freely.

    The right to assemble and to protest is an essential part of any functioning democracy. Remember the mass civil unrest that was occurring in Hong Kong and France before Christmas? This has disappeared without a trace. Are we no longer allowed to march on the streets should the need to protest arise? What is now stopping future governments using the ‘health and safety’ of the public as an excuse to crack down on civil disobedience?

    1. The right to free speech. 

    One of the most important of our human rights, established as early as 1789 in Article XI of the French ‘Declaration of the Rights of Man’ – ‘The free communication of thoughts and of opinions is one of the most precious rights of man: any citizen thus may speak, write, print freely’. Article 40.6.1 of the Irish Constitution guarantees a right to express freely  your convictions and opinions .

    However, this right has come under attack in recent months, with censorship becoming very prevalent. Any questioning of the mainstream narrative quickly gets labelled ‘false news’ or a ‘conspiracy’ theory, thereby stifling debate and discussion. Who has the power to decide what is false news? Do you, or do I? Or does some unelected Youtube or Google content executive?

    The mainstream media and social media companies have unprecedented power to manipulate the narrative. Social media and search engine algorithms can effectively control what we read and see, and therefore control the reality we live in. Who decides what we should think, and who holds this absolute and terrifying power?

    I may not agree with what you are saying, but I absolutely respect your right to say it. Otherwise, one day, we may find that right has been taken from us.

    1. The right to privacy.

    Article 8 of the European Convention on Human Rights states that ‘Everyone has the right to respect for his private and family life, his home and his correspondence.’

    The seemingly benign concept of using a ‘contact tracing’ app could easily be misused by governments to normalise mass surveillance of citizens at all times, in the interests of public safety. Keeping track at all times of where you go and who you are with, a smartphone becomes like a voluntary ankle tag. With smartphones becoming almost essential to function in society, this mass surveillance is constant.

    One of the very worst tendencies this crisis has brought out in people is of of neighbours spying on one another, settling old grievances by informing. Have people forgotten already how secret police, such as the Stasi in East Germany, controlled populations by encouraging this behaviour?

    The French philosopher Michel Foucault believed that: ‘the power of a goverment is co-extensive with its ability to surveil’,  and wrote about the symbolic prison of the Panopticon, in which prisoners never knew when they were being observed, so were obliged to be on their best behaviour at all times. We are living in a digital panopticon, and giving governments unprecedented powers of surveillence.

    Inside one of the prison buildings at Presidio Modelo, Isla de la Juventud, Cuba.

    Moreover, with cash becoming redundant through this crisis, governments and corporations have acquired an even greater capacity to surveil, and therefore control, our lives. In the U.K., Derbyshire police used drones to film hillwalkers in a remote mountain area, while in California police fined surfers a $1000 for catching waves.

    Is this the kind of society you want to live in?

    1. The right to bodily autonomy and personal sovereignty.

    Are we going to give away our right to bodily autonomy to pharmaceutical companies, and the possibility of a mandatory vaccination programme?

    I am neither pro- nor anti- vaccination, but I believe that people should enjoy an absolute right to decide what is put into their bodies, freedom over their own body. A right to bodily integrity has been recognised by the courts as an unenumerated right, protected by the general guarantee of ‘personal rights’ contained under Article 40 of the Irish constitution.

    There is some disagreement in the scientific community around the safety of vaccines, with billions of dollars having been paid out in compensation by the Vaccine Injury Courts over the past thirty years, but any dissent of the mainstream Big Pharma narrative is brutally suppressed and attacked. In the Middle Ages, heretics were burnt at the stake for daring to question the mainstream version of reality. While they are not burnt at the stake today, anyone who questions the mainstream narrative is attacked, vilified, and discredited

    If anyone thinks these concerns over civil liberties far-fetched, I suggest you look at the situation in China at the moment, where the government has used the crisis to strengthen its grip on power, and to crack down on dissent.

    Dmytro Sidashev / Alamy Stock Photo

    What sort of world do we want to live in post-Covid-19?

    I would easily sacrifice an element of safety for my freedom. I want to live in a world where personal liberty and civil duties are both honoured and respected; where personal sovereignty is not given away to unelected global corporations; where political power remains vested in individuals and communities, and a central State does not have unchecked power to interfere in citizens’ lives. Where policing is by consent, and not by coercion and control. I want young children to be able to run freely in the outdoors without fear, or masks.

    Image: Daniele Idini (c)

    I do not want to die anytime soon, but if I do, so be it. I have long accepted that one day I will die. I would much rather die a free man from Covid-19 than live in a dystopian surveillance society. What we are seeing is a global collective psychological process, the unconscious and unprocessed fear of death. By facing and accepting our own mortality, this fear dissipates.

    I do not want to live in a sanitised, risk-free, nanny-state surveillance world, where the government knows where I am at all times and controls what I think, what I can say, what I put in my body. I do not consent to this version of reality. I will not be part of it.

    The real front line is about personal power and self-sovereignty. Reclaiming our power from the unelected Silicon Valley AI/tech, media and pharmaceutical executives, who have acquired greater power over every aspect of our lives, with hardly any oversight.

    We need to come terms with the immense power that is accumulating in Google and Facebook to influence, manipulate and control what people think. Even that most Machiavellian of realpolitik bureaucrats Henry Kissinger recently wrote: ‘The Age of Reason originated the thoughts and actions that shaped the contemporary world order. But that order is now in upheaval amid a new, even more sweeping technological revolution whose consequences we have failed to fully reckon with, and whose culmination may be a world relying on machines powered by data and algorithms and ungoverned by ethical or philosophical norms’. He who controls the algorithms controls the world.

    This is not a world I want to create. I do not consent. For sure this crisis has brought out the very best in humanity, with neighbours helping one another, communities coming together, increasing food security and developing a great sense of solidarity. But we cannot, Pollyanna-like, ignore the potential for the slide into a dystopian surveillance society.

    What sort of society do we want our children and grandchildren to inhabit? This is the real front line. We have had a great opportunity for reflection and collective dreaming, for visioning and birthing a new society and new reality. The birthing process of the new world will be messy and painful, as births always are, but the baby will be born.

    We are not powerless. We have the power to rewrite the story and create a beautiful world for future generations. Let us make our collective vision a beautiful one.

    Image: Daniele Idini (c)